2:00 Assessing Bifunctional Protein Degraders for Oral Delivery

Time: 9:30 am
day: Day 1 Track A morning


  • Understand why bifunctional protein degraders cannot be evaluated through a conventional small molecule lens
  • Explore the key physicochemical properties that determine whether a bifunctional protein degrader is likely to be orally bioavailable
  • Discuss rate limiting steps to oral absorption and how enabling technologies may enhance absorption of this class of molecule