2:00 PROTAC Discovery – Why is PK/PD Modelling Essential?

Time: 9:30 am
day: Day 1 Track B morning


  • How can PK/PD modelling inform experimental study design and data evaluation both in vitro and in vivo ?
  • What are the parameters that make an efficient degrader ?
  • How can we link target degradation in vitro to pharmacodynamic effects and how can we translate this to the in vivo situation ?