Decoding Ternary Complex Formation to Advance Mechanistic Understanding in Molecular Glue Discovery

  • Elucidating the mechanistic drivers of ternary complex formation to improve predictability in molecular glue discovery
  • Designing assays that detect and stabilise protein–protein interactions under the right biophysical conditions to enhance screening accuracy
  • Applying mechanistic insights to build models that guide hit identification and inform future induced proximity modalities beyond molecular glues

New Data