Correlating Cellular PROTAC-induced Ternary Complex Formation with Degradation Outcomes
Time: 10:30 am
day: Day One
Details:
- Translating PROTAC med chemical series optimization into functional degradation outcomes
- Predicting target protein ubiquitination with ternary complex ensemble modeling and correlation with cellular studies
- Trivalent PROTACs and live cell monitoring of ternary complex avidity and cooperativity
