Correlating Cellular PROTAC-induced Ternary Complex Formation with Degradation Outcomes

Time: 10:30 am
day: Day One

Details:

  •  Translating PROTAC med chemical series optimization into functional degradation outcomes
  • Predicting target protein ubiquitination with ternary complex ensemble modeling and correlation with cellular studies
  • Trivalent PROTACs and live cell monitoring of ternary complex avidity and cooperativity

Speakers: