Developing Bispecific Antibody Degraders to Achieve Tissue-Specific Degradation of Membrane Proteins

  • Engineering bispecific antibody degraders to enable selective, lysosomal degradation of target membrane proteins
  • Pairing therapeutic targets with membrane E3 ligases to achieve tissue-specific degradation while sparing healthy tissues
  • Expanding therapeutic reach to hard-to-drug and challenging membrane targets

New Data