Discovering & Validating Novel E3 Ligases to Expand Degrader Utility & Achieve Proof-of-Concept Across Diverse Targets

  • Applying phenotypic and functional genomics screens to uncover novel E3 ligases with translational relevance
  • Establishing mechanistic and in vivo validation to demonstrate degrader efficacy and tissue selectivity
  • Exploring the potential for broad target applicability and therapeutic versatility of emerging ligase systems

New Data

Noval Ligase