As degraders expand into non-oncology indications, this workshop will show you how autophagy-mediated and molecular glue approaches are being applied to tackle neurodegenerative diseases and other biologically complex conditions.

We will cover:

• Demonstrating the role of molecular glue–mediated stabilisation in restoring proteostasis in tau, α-synuclein, and LRRK2-driven neurodegeneration
• Showcasing the bimodal mechanism-of-action of the AUTOTAC platform in targeted protein degradation and selective autophagy activation, with a focus on translation of basic research findings for drug discovery
• Autophagy-mediated clearance of pathological protein aggregates in neuronal models of neurodegenerative diseases

This workshop is ideal for biologists and chemists exploring TPD approaches in non-oncology settings, from target selection to translation.

New Data