Harnessing Molecular Glue–Mediated Stabilisation to Restore Proteostasis & Expand Induced Proximity Beyond Degradation
- Exploring induced proximity mechanisms that stabilise protein–protein interactions to restore proteostasis in neurodegeneration and cancer
- Applying structure-guided chemistry and biophysical characterisation to optimise cooperativity and target engagement in molecular glue design
- Discussing how Ambagon’s platform expands induced proximity beyond degradation to address disease-agnostic biological pathways