Harnessing Molecular Glue–Mediated Stabilisation to Restore Proteostasis & Expand Induced Proximity Beyond Degradation

• Exploring induced proximity mechanisms that stabilise protein–protein interactions to restore proteostasis in neurodegeneration and cancer
• Applying structure-guided chemistry and biophysical characterisation to optimise cooperativity and target engagement in molecular glue design
• Discussing how Ambagon’s platform expands induced proximity beyond degradation to address disease-agnostic biological pathways

Speakers:

Christian Ottmann

Co-Founder & Chief Scientific Officer

Ambagon Therapeutics