Round Table Discussion: Examples of Degraders Entering the CNS

Time: 2:00 pm
day: Day 2 PM - Stream B


  • What E3 ligase was utilised?
  • What does the structure of the PROTAC look like?
  • What are the main challenges of delivering protein degraders across the blood brain barrier and how is this overcome?
  • What are the druggable and undruggable targets within neurodegenerative disease that could be targeted with protein degradation strategies?