Targeted Protein Degradation in Escherichia coli Using CLIPPERs
Time: 1:30 pm
day: Pre-Conference Day
Details:
- CLIPPERs are peptides that bridge the bacterial ClpXP protease to the Target
- CLIPPERs cause degradation of endogenous target proteins in Escherichia coli
- Degradation of essential target proteins by CLIPPERs has an antibacterial effect
