Benedict Cross

Company: PhoreMost

Job title: Chief Technology Officer & Head of Platform

Seminars:

Molecular Glue Discovery by High-Throughput Neomorphic Remodelling of Effector Proteins 2:15 pm

MThe promise of new medicines that operate through induced degradation has been stunted by a scarcity of systematic tools that can uncover the relevant design principles Here we introduce GlueSEEKER®: an intramolecular editing-based screening system to remodel the surface landscapes of E3 ligases We show that effector proteins can be re-engineered to produce neomorphic activity…Read more

day: Day 1, Track 1, PM