Carlos Martinez Fleites
Scientific Leader, Molecular Modalities Discovery GlaxoSmithKline
Seminars
Wednesday 11th March 2026
Decoding Ternary Complex Formation to Advance Mechanistic Understanding in Molecular Glue Discovery
11:30 am
- Elucidating the mechanistic drivers of ternary complex formation to improve predictability in molecular glue discovery
- Designing assays that detect and stabilise protein–protein interactions under the right biophysical conditions to enhance screening accuracy
- Applying mechanistic insights to build models that guide hit identification and inform future induced proximity modalities beyond molecular glues
New Data