Giovanni Spagnolli
Seminars
Thursday 12th March 2026
Optimal Drug-Like Properties for Cyclin D1 Degradation
1:10 pm
- Leveraging Sibylla’s platform to design folding-interfering molecules that disrupt protein folding pathways for targeted degradation
- Optimising compounds for potent Cyclin D1 degradation and favourable ADME profiles to enable therapeutic development
- Sharing in vitro and in vivo validation data to support translational development of folding interfering molecules targeting Cyclin D1
