Hongbo Zhang
Chief Scientific Officer & Head of Drug Discovery Service HitChem
Seminars
Wednesday 11th March 2026
From Design to Application: A CRBN Molecular Glue Library Derived from In-House and Literature-Validated CRBN Binders
4:15 pm
- A systematic exploration of the chemical space of CRBN-binding scaffolds (300 compounds synthesized and tested)
- SAR insights and highlighting representative, structurally novel, and effective binders.
- An overview of HitChem’s CRBN molecular glue library design strategy and HTS case studies on multiple targets
