Lukas Junk

Lukas Junk

Company: Helmholtz-Institute for Pharmaceutical Research Saarland

Job title: Postdoctoral Researcher


BacPROTAC-induced degradation of ClpC1 as a new strategy against drug-resistant mycobacteria 3:30 pm

Hijacking the mycobacterial protease ClpC1:ClpP1P2 offers unique opportunities to overcome antimicrobial resistance Outlining the development of natural product-inspired degraders, “BacPROTACs” that bind to the substrate receptor of the ClpC1:ClpP1P2 protease, priming neo-substrates for degradation. Reviewing the degradation and anti-mycobacterial properties of homo- BacPROTACs that induce the degradation of ClpC1 in Mycobacterium tuberculosisRead more

day: Pre-Conference Day

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