Randolph Lopez

Company: A-Alpha Bio Inc.

Job title: Co-founder & Chief Technology Officer

Seminars:

Discovering & Characterising Basal Protein-Protein Interactions Across 200 Therapeutic Targets 1:45 pm

Over 500 basal protein-protein interactions were identified between therapeutically relevant targets and a diverse array of ligases and chaperone proteins A subset of these interactions was further characterised through site-directed mutagenesis to define the PPI interfaces and explore the potential for affinity modulation These protein-protein interactions were subsequently prioritised to guide small molecule discovery campaigns…Read more

day: Day 1, Track 1, PM