NEOsphere Biotechnologies
Expertise Partner
NEOsphere Biotechnologies pioneers proteomics for TPD drug discovery. Our target and E3 ligase-agnostic high-throughput proteomic screening platform creates broad pipelines of novel degrader targets at scale and advances drug discovery at all stages. Cutting-edge mass spectrometry and expert data analysis characterize entire libraries of protein degraders in native cells and identify molecules acting through new E3 ligases and TPD mechanisms; global ubiquitinomics mechanistically validates degrader-induced modifications to an unparalleled depth.
WuXi AppTec
Exhibition Partner
WuXi AppTec provides a full spectrum of services to support research focused on targeted protein degradation. Our discovery platform allows for in-depth biological and biophysical characterization of bifunctional molecules. We offer proximity assays to measure ternary complex formation, target protein ubiquitination and degradation assays, and high-resolution X-ray crystallography of binary and ternary complexes. Our platform also includes extensive chemistry services, such as custom synthesis, scale-up, and purification of new linkers and E3 ligase ligands.
HYBRIGENICS SERVICES
Event Partner
Hybrigenics Services, with 25+ years of expertise in advanced Y2H technology, offers the Y2HChem screening platform to identify protein-protein interactions induced or stabilized by molecular glues or bifunctional molecules. Y2HChem screens are conducted on the entire proteome using one of our 135+ libraries or a newly developed human E3 ligases library, enabling the discovery of substrate-E3 ligase interactions. With over 600 customer publications, we are recognized as a trusted scientific partner in providing high-quality and reliable results.
PHARMARON
Event Partner
At Pharmaron, we're a leading contract research organisation known for our extensive laboratory services and expertise in Target Product Degradation (TPD). With advanced facilities and a dedicated team, we specialise in customised solutions for drug discovery and development. Our TPD capabilities allow for precise evaluation of drug stability and efficacy, ensuring the delivery of top-quality pharmaceuticals. With a track record of supporting over 2000 organisations globally, we've become a trusted partner in the biopharmaceutical field.