We share your passion for science. Promega is committed to excellence in technologies to assess key processes in PROTAC- and molecular glue-induced protein degradation. From assessing protein degradation in real time, to ternary complex formation and more. Our CRIPSR content covers hundreds of pre-built targets. Assay live cells in kinetic mode to determine target protein degradation rates, DC50 potency values, and recovery profiles. Let’s collaborate.
HitGen, Inc. is a biotech company focused on DNA Encoded Library development and applications. HitGen's DELs currently contain more than 400 billion novel, diverse and drug-like small molecules, which are synthesized from many hundreds of distinct chemical scaffolds, designed with tractable chemistry, and have yielded proven results on challenging targets such as PPI with high affinity. HitGen has also developed unique DELs and methods for identification of small molecules that can be used for targeted protein degradation.
Selvita is an integrated service company providing multidisciplinary support in resolving the unique challenges of research within area of drug discovery, regulatory studies, as well as research and development. The company was established in 2007 and currently employs 450 professionals.
Specialising in delivering integrated solutions Selvita has a proven track record of not just providing scientific excellence, but on building long-term partnerships with our clients and playing an active, consultative role in the project execution.
We are a CRO specialising in the analysis of proteins and their associated PTM’s via advanced Mass Spectrometry. By using proprietary methodologies, we can detect up to 8,000 proteins per sample in Discovery mode and can offer multiplexed assays of up to 100 proteins/sample in a GCLP accredited Targeted assay.
With their proprietary bioinformatics software, these can be trimmed down to some tens of proteins that are either up-, or down-regulated with disease progression or drug treatment.
Aurelia Bioscience is a UK based pre-clinical contract research organisation specialising in bioassay development, pharmacological profiling and compound screening. Scientists at Aurelia Bioscience have significant experience of different target classes and use cutting edge technologies to deliver client projects in a timely, efficient and cost-effective manner. They work in early stages of the drug discovery pipeline including target identification and validation, hit identification, hit to lead as well as lead identification and optimisation.