Deep Proteomic Screening for Systematic Discovery of Novel Degrader Targets
Time: 11:45 am
day: Day 1 Track A AM
Details:
- High-throughput proteome-wide degrader characterization with unparalleled sensitivity, data completeness, and turnaround times
- Identification of novel degrader targets, monitoring of proteome-wide selectivity, and detection of molecules acting through new E3 ligases and emerging TPD mechanisms.
- Demonstration of degrader-induced modification by ubiquitinomics to a depth of up to 50.000 sites and detection of degrader-induced E3 ligase binding by interactomics
