Bifunctional Degrader Discovery with PROTEINi Screening
Time: 1:45 pm
day: Day 2 Track A PM
Details:
- Performing phenotypic screening for protein degraders using PhoreMost’s PROTEINi technology has identified several novel bio-active degron peptides and their corresponding E3 ligases
- Harnessing target-specific screening to allow the development of biological bifunctional protein degrader molecules
- Showcasing how PROTEINi/E3 ligase interaction can be used to inform and accelerate the development of small molecules that interact with E3 ligases and build novel heterobifunctionals
