From Ligases to Molecular Glues – Strategies to Discover Novel Molecular Glues
Time: 1:15 pm
day: Day 1, Track 1, PM
Details:
- Advancing E3 ligase ligand discovery through cutting-edge techniques to identify high-affinity, selective ligands that serve as the foundation for novel degraders
- Transforming ligase ligands into functional molecular glues, engineering them to precisely target and modulate protein-protein interactions for therapeutic benefit
- Pioneering new approaches to develop molecular glue degraders, unlocking unique pharmacological effects to address previously undruggable targets and expand therapeutic possibilities
