Novel E3 Ligase-Based Targeted Protein Degradation: Potential Applications Within & Beyond Cancer Therapy
Time: 4:45 pm
day: Day 1, PM
Details:
- Somatic mutation of some E3 ligases create novel E3 ligase that do not exist in normal tissues
- Targeted protein degradation using the mutated E3 ligases are very specific and only happen with the presence of the mutated E3 ligase
- Novel E3-based TPD and potential applications are discussed with an example
