Panel Discussion: Assessing Targeted Protein Degradation’s Ability to be Both Selective & Safe
Time: 9:45 am
day: Conference Day One
Details:
- How much progress has been made in identifying and utilising tissue-sparing E3 ligases? Are there more ligases to find? How do we effectively identify them?
- What does existing off-target safety data tell us about degraders’ behaviour in clinic?
- Are Molecular Glues a ‘safer’ option? Are there other ‘TACs’ that have potential to be safer due to their MOA?