SureTACsTM: Beyond Blocking Membrane Proteins
Time: 11:30 am
day: Day 2, Track 2, AM
Details:
- Membrane-bound E3 ligases can be repurposed for the targeted degradation of disease-driving cell surface proteins
- Laigo Bio’s TED-I screening platform is essential to identify optimal E3-target pairs with highest degrader potency
- SureTACsTM: bispecific antibodies that induce cell surface removal and target degradation in a tissue- and disease-specific manner
