Giovanni Spagnolli

Company: Sibylla Biotech srl

Job title: Chief Technology Officer

Seminars:

PANEL DISCUSSION Clear Skies or Stormy Seas: Sailing the European Markets in Search of Funding & Partnerships for Effective Degrader Development 8:45 am

What are the trends in the current European investment environment, and how can emerging companies effectively demonstrate commercial viability in these conditions? What is the average European life sciences VC’s risk appetite, and how can biotechs navigate this to secure investment? How do the dynamics of biotech-to-biotech deals compare to pharma partnerships? Does Europe need…Read more

day: Day Two Until 10am

Developing Optimised Folding Interfering Degraders Targeting Cyclin D1 11:45 am

Providing an overview of folding interference as a new modality to induce the degradation of a target protein Demonstrating that folding interfering degraders (FIDs) can be optimised to achieve high potency and desirable ADME properties Showing in vitro and in vivo characterisation of FIDs acting on Cyclin D1Read more

day: Day 1, Track 2, AM