Job title: Group Leader of Functional Proteomics
Kristin received her PhD in Biomedical Engineering from the University of Wisconsin – Madison, where she studied the structural and mechanical properties of collagen fibers and their effects on breast cancer cell migration in invasive ductal carcinoma. She joined Promega in 2014 as a postdoctoral researcher and is currently a Senior Scientist developing technologies to characterize degradation and protein interactions within the ubiquitin proteasomal pathway in living cells.
Cellular Mechanistic Profiling of Degradation Compounds 9:30 am
Several case studies to understand PROTAC mechanism of action in different systems Correlation of real-time kinetic degradation profiles to ternary complex formation and ubiquitination Cell-based assay strategies for rank ordering compound potency and efficacyRead more
day: Day One