Zhangping Xiao

Company: Imperial College London

Job title: Marie Curie Fellow Postdoc, Tate Group

Seminars:

Identification of PROTAC-able Sites on Protein Degradation Effectors Through Site-Specific Ligand Incorporation-Induced Proximity (SLIP) 3:45 pm

More TPD effectors and their ligands are needed SLIP is a powerful platform to create proximity in live cells SLIP enabled identification of PROTACable sites on TPD effectorsRead more

day: Day 1, PM

Novel E3 Ligase-Based Targeted Protein Degradation: Potential Applications Within & Beyond Cancer Therapy 4:45 pm

Somatic mutation of some E3 ligases create novel E3 ligase that do not exist in normal tissues Targeted protein degradation using the mutated E3 ligases are very specific and only happen with the presence of the mutated E3 ligase Novel E3-based TPD and potential applications are discussed with an exampleRead more

day: Day 1, PM