Swen Hoelder

Company: The Institute of Cancer Research

Job title: Professor & Interim Director

Seminars:

A Tricycle Journey to in-vivo Degraders of the Oncogenic Transcription Factor BCL6 12:15 pm

BCL6 is an oncogenic transcriptional repressor upregulated in a large fraction of diffuse large B cell lymphomas (DLBCL) We discovered potent BCL6 inhibitors. Some inhibitors triggered degradation of BCL6. We elucidated the structural requirements for degradation enabling the discovery of a potent in vivo degrader of BCL6Read more

day: Day 1 Track B AM